Loyiso Madinga started comedy in June 2012 at AWEdnesday Comedy Jam. One month after that he entered the Parkers Comedy competition and won it. Through this, he was put on the line up for the Nando’s Comedy at the Teatro, Monte Casino, alongside David Kau, Ian Bagg, Mith Fatel, Brian Haner, Christina Pizsitzky, Tom Segura and Finesse Mitchel. He was then asked to join the Soweto leg of the Nando’s Comedy event that included David Kau, Brian Haner, Lil Rel, Loni Love, Orlando Jones, and Michael Winslow. Loyiso Madinga was then part of the line up for David Kau’s Blacks Only at Carnival City on the 27th October 2012 alongside Jason Goliath and Skhumba Hlope. He has gone on to perform at various comedy events including Parker’s comedy club, The Box at POPArt theatre and Primi’s Comedy Wednesday in Rosebank, and Comedy at 2013.